重組人β-NGF(β神經生長因子)
中文名稱：重組人β-NGF(β神經生長因子)英文名稱：Recombinant Human beta-Nerve Growth Factor產品規格：10μg|50μg|500μg|1mg
大腸桿菌表達系統制備，目的基因編碼的Ser122-Ala241表達純化而來。
beta-NGF質量控制：＞95%(還原性SDS-PAGE)。
beta-NGF制劑：凍干品
beta-NGF保存：
凍干蛋白可在-20℃長期保存，室溫也可穩定保存3周。
復溶蛋白溶液可在4～7℃保存2～7天。
復溶后建議分裝凍存在-20℃，可保存3個月，應避免反復凍融。
beta-NGF復溶：
1、試劑開蓋前請先離心。
2、復溶濃度應大于100 μg/ml.
3、凍干蛋白溶于ddH2O中
4、復溶后根據使用量分裝保存，避免反復凍融。
關于beta-NGF：
Human β-Nerve Growth Factor (β-NGF) was initially isolated in the mouse submandibular gland. It is composed of three non-covalently linked subunits α, β, and γ; it exhibits all the biological activities ascribed to NGF. It is structurally related to BDNF, NT-3 and NT-4 and belongs to the cysteine-knot family of growth factors that assume stable dimeric structures. Β-NGF is a neurotrophic factor that signals through its receptor β-NGF, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. These results suggest that β-NGF is a pleiotropic cytokine, which in addition to its neurotropic activities may have an important role in the regulation of the immune system. Human β-NGF shares 90% sequence similarity with mouse protein and shows cross-species reactivity |
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