重組人IGF-I(胰島素樣生長因子I)
中文名稱:重組人IGF-I(胰島素樣生長因子I)英文名稱:Recombinant Human Insulin-Like Growth Factor I產品規格:10μg|50μg|500μg|1mg
大腸桿菌表達系統制備,目的基因編碼的Thr52-Ala118表達純化而來。
IGF-I質量控制:>95%(還原性SDS-PAGE)。
IGF-I制劑:凍干品
IGF-I保存:
凍干蛋白可在-20℃長期保存,室溫也可穩定保存3周。
復溶蛋白溶液可在4~7℃保存2~7天。
復溶后建議分裝凍存在-20℃,可保存3個月,應避免反復凍融。
IGF-I復溶:
1、試劑開蓋前請先離心。
2、復溶濃度應大于100 μg/ml.
3、凍干蛋白溶于ddH2O中
4、復溶后根據使用量分裝保存,避免反復凍融。
關于IGF-I:
Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone |
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